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KMID : 1161420210240060577
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Journal of Medicinal Food
2021 Volume.24 No. 6 p.577 ~ p.585
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Improvement of Fatigue Symptoms and Endurance Capacity by the Combined Administration of Cervus elaphus L., Angelica gigas Nakai, and Astragalus membranaceus Bunge
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Huang Wen Yan
Youk Jin-Soo
Han Bok-Kyung
Heo Wan
Yun Beom-Sik
Kim Jin-Soo
Koo Young-Tae
Hwang Kyung-A
Yoon Jin-A
Kim Young-Jun
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Abstract
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Fatigue is a common phenomenon usually observed in healthy, as well as in nonhealthy, individuals that affects their performance and quality of life. Efficient supplementation to relieve fatigue is of significant importance. This study was designed to investigate the efficacy of three prescreened natural resources (Cervus elaphus L. [CEL], Angelica gigas Nakai [AGN], and Astragalus membranaceus Bunge [AMB]) against fatigue symptoms induced by heavy exercise. Effects on muscle fatigue and endurance capacity during exercise were investigated in C2C12 myoblasts and exercised mice. A combination of CEL, AGN, and AMB (CEL:AGN:AMB, 1:2:1) treatment in myoblasts reduced intracellular reactive oxygen species levels induced by hydrogen peroxide by ∼20 times (P?
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KEYWORD
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Angelica gigas Nakai, antifatigue, antioxidant, Astragalus membranaceus Bunge, Cervus elaphus L., endurance capacity
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